T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model
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چکیده
منابع مشابه
T cell--associated immunoregulation and antiviral effect of oxymatrine in hydrodynamic injection HBV mouse model
Although oxymatrine (OMT) has been shown to directly inhibit the replication of hepatitis B virus (HBV) in vitro, limited research has been done with this drug in vivo. In the present study, the antiviral effect of OMT was investigated in an immunocompetent mouse model of chronic HBV infection. The infection was achieved by tail vein injection of a large volume of DNA solution. OMT (2.2, 6.7 an...
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Hepatitis B virus (HBV) reactivation and recurrence are common in patients under immunosuppression and can be controlled by hepatitis B immunoglobulin, antivirals, and hepatitis B vaccine. However, the detailed analysis of HBV infection under immunosuppression is essential for the prophylaxis and therapy for HBV reactivation and recurrence. In this study, HBV replication and T cell responses we...
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ژورنال
عنوان ژورنال: Acta Pharmaceutica Sinica B
سال: 2017
ISSN: 2211-3835
DOI: 10.1016/j.apsb.2017.02.005